Economic aspects 
    Economic aspects of the HIV/AIDS epidemic refer to utilisation of inpatient and outpatient
    care, drugs and the costs associated. Economic impact assessment is done for the purpose
    of cost-effectiveness analysis, where health-care inputs are related to health gains (i.e.
    prevented transmissions, delayed AIDS cases and gained life years).  
    
      - Highly active anti-retroviral treatment (HAART)
        appeared to be as an important topic for cost-effectiveness. Increasing use of HAART has
        been associated with a reduction of inpatient costs.
 
     
    
      - Many studies report major increases in the
        utilisation and costs of drugs after the introduction of protease inhibitors. 
 
      - More people with HIV/AIDS are receiving
        anti-retroviral therapy. In France, persons on treatment increased from 60 to 90%. 
 
     
    
      - Major problems concerning affordability are
        reported for developing countries. In India, a study reports that only 2.8% of patients
        can afford combination therapy.
 
     
    Bridging session : Implications of
    therapies for developing countries 
    
      - Given scarce resources, countries have to make
        choices. If brutal choices are not made now, in the future they will be even more brutal. 
 
      - For many countries, in addition to the fight
        against AIDS, governments have many other developmental objectives. They are confronted
        with diseases such as malaria, tuberculosis, other STDs, and increasingly chronic
        diseases. Choices have also to be made between different areas of development. 
 
      - According to the World Bank, treating one patient
        with AIDS is as expensive as giving 10 children primary health education. The list of
        competing alternatives is almost endless, for example, basic access to water and food,
        access to primary health care and essential drugs, rehabilitation after internal wars and
        conflicts.
 
      - In many regions of the world, opportunistic
        infections treatments, anti-retroviral drugs, and palliative care treatments are not
        available. 
 
     
    
      - In order to implement any program, there needs to
        be a stable health services infrastructure, which is lacking in many countries but it is
        possible to establish a network of services. In Brazil, 58,000 persons take
        anti-retroviral therapy now. The costs increased from $ 37/mo in 1996 to an estimated $
        600/mo in 1999. 
 
      - Unfortunately many countries set other priorities.
 
     
    
      - Pharmaceutical companies can make a contribution,
        by lowering the prices : 
 
      - The differences in prices are shameful. In Mexico,
        AZT costs less than $0,50 while it is almost $7 in Brazil. Intravenous AZT costs $6 in
        Brazil and almost $50 in Mexico. The costs of triple therapy in different Latin America
        countries range from $7,000 in Costa Rica to $16,000 in Uruguay. 
 
      - Pharmaceutical companies have mission statements.
        But words are not enough, where action is needed. Pharmaceutical companies should no
        longer focus on shareholder-value. Stakeholder-value is tomorrows management
        keyword.
 
     
    International Funding and Policy 
    
      - The case of Thailand showed how the Asian
        financial crisis is affecting their National Program and their ability to face the AIDS
        crisis. The Canadian representative spoke about participating to support international
        development.
 
     
    
      - Bernard Kouchner, the French health minister,
        reiterated an important announcement. France is taking the leadership in an effort to
        create an international partnership with other industrialised countries to help fund
        antiretroviral medication for poor countries. This proposal has been taken to the European
        Parliament and to the G 8. 
 
     
    
      - Callisto Madavo from the World Bank gave a
        comprehensive explanation on why AIDS was a development issue. He offered suggestions of
        what African governments could do to implement more effective policies in the fight
        against AIDS. He also urged the World to help in the solution. 
 
     
    
      - Dr Jonathan Mann presented a very compelling
        presentation on how prevention continues to be the most important tool against the AIDS
        epidemic. He argued that the two most powerful prevention agendas today were finding an
        effective vaccine and creative social change, based on human rights. 
 
     
    Gender and Power 
    Participants agreed on the importance of analysing the way socially constructed male and
    female roles are affecting the spread of AIDS.  
    
      - Gender roles are not biologically determined but
        socially constructed. 
 
      - Gender is the set of norms, prescriptions and
        cultural representations that a society dictates for male and female behaviour. This
        varies in different societies, social classes and regions of the world, but in general
        determines differences of what is expected of men and women and tends to establish both
        stereotypes for each sex and double moral standards. This is the basis on which much of
        the inequality between men and women is established. 
 
     
    The projects presented in this
    session were a very vivid example of how these theoretical principals play out in
    different countries. 
    Coping strategies: Individuals,
    families and organisations 
    Home care is often promoted as an alternative,
    particularly in developing countries; but the home is not necessarily the safest place for
    PWAs. Discrimination also often happens at home. Individuals and their families must
    receive support in order to create the environment needed by PWAs to improve their quality
    of life. Organisations develop programs that are often articulated around the following
    issues: 
    
      - Training and counselling for individuals and their
        families (including children);
 
      - Information and discussion on stressful situations
        in the family;
 
      - Sex after diagnosis;
 
      - Care for dependants, children in particular.
 
     
    Promotion of community coping
    strategies should NOT mean a simple shift of burden to families and communities. Women can
    easily be overburdened. They must be empowered in their different roles. PWAs are also
    potential care givers and agents of change, and their involvement is crucial for the
    success of coping strategies.  
    Evaluation Methodology 
    
      - Recommendations included the need to establish
        clear standards for program evaluation, more consistent publication guidelines, and more
        studies of this type. 
 
      - Interventions aimed at enhancing evaluation skills
        in NGOs can improve the delivery of programs. 
 
      - One study compared behavioural with biological
        indicators of sexual risk. The results suggest that, while self-reported behavioural
        change may predict risk reduction, it usually does not if measured by objective measures.
        Another study, focusing on studies of sero-discordant heterosexual couples, underscored
        the need for more careful exploration of risks and behaviours, and raised doubts on
        whether all the necessary questions on risky behaviours are in fact being asked in current
        studies.
 
     
    HIV Transmission: Infant Feeding 
    Although vertical transmission through breast milk
    was identified in 1985, there have been many complex issues surrounding the recommendation
    of artificial feeding.  
    
      - For HIV-positive mothers, information on
        artificial breast-feeding is essential since it can prevent the childs infection.
        Each woman should have a possibility of informed choice. For artificial feeding to be
        effective mothers need clean water, the knowledge on the how to sterilise utensils and
        prepare the formula. 
 
      - The widespread use of artificial feeding by
        HIV-negative mothers and women unaware of their status can increase malnutrition and
        mortality. Infant mortality is 16 times more likely with artificial feeding than if a
        child is breast-fed. 
 
     
    The artificial feeding business
    should consider: 
    
      - Emphasis on replacement feeding as a medicinal
        practice;
 
      - Procuring the formula centrally to control
        its distribution;
 
      - Arrange for generic packaging so as not to promote
        the product.
 
     
    For successful artificial feeding
    there is a need for education on alternatives such as cow and goats milk, expressing
    breast milk and boiling it and, if available, the use of an HIV-negative wet nurse. Making
    the change from the emotional rewarding act of breast feeding to artificial feeding often
    is an enormous burden for the mother to carry. Comprehensive education, emotional support
    and access to different options are needed.  
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